Dengue infection is caused by 4 antigenically distinct dengue virus serotypes: DENV-1, DENV-2, DENV-3, and DENV-4. Severe dengue most commonly occurs among infants and patients with secondary dengue virus (DENV) infections (i.e., infection with a DENV type different from what they were previously infected with earlier in life). Female mosquitoes, predominantly of the species Aedes aegypti and less commonly, Aedes albopictus, The pathophysiology of dengue especially dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS) were rarely known; as a result, it was seen as deadly by some but was also perceived as easily curable by others without a basis of understanding. This helps you give your presentation on Dengue Fever in a conference, a school lecture, a business proposal, in a webinar and business and professional representations.. I. Fever is the elevation of the body's temperature above the normal level. Dengue hemorrhagic fever is caused by a bite of a vector mosquito called, Aedes Aegypti. Dengue fever is a mosquito-borne viral disease caused by 1 of 4 closely related but antigenically distinct serotypes of dengue virus, serotypes DENV-1 … This mosquito is considered to be a day- biting and low flying mosquito and commonly be found inside the household. pathogenesis and pathophysiology of dengue fever and dengue … Confirmed Dengue Fever!-4 -2 02 46 81 01 2 Febrile Phase Critical Phase Recovery Phase Viremia NS1a ntigen Mosquito bite IgG IgM Fever Shock Bleeding days A B FIGURE 1. ISBN: 978-1-908978-79-0 (ebook) Checkout. For more information and source, see on this link : https://www.slideshare.net/fareedresidency/dengue-fever-pharmacy-presentation dengue fever; however, as the fever declines, symptoms quickly progress to include frequent vomiting, severe stomach pain, difficulty breathing and significant bleeding. Dengue and dengue hemorrhagic fever (DHF) result from infection by any of four serotypes of dengue viruses. If the address matches an existing account you will receive an email with instructions to reset your password Symptoms of dengue fever: In case of severe pain or fever you can take paracetamol. According to the Pan American Health Organization (PAHO), the clinical description of dengue fever is an acute febrile illness of 2-7 … Researchers have made unremitting efforts over the last half-century to understand DHF pathogenesis. Dengue fever is a disease caused by a family of viruses transmitted by mosquitoes. Dengue Virus

• Causes dengue and dengue hemorrhagic fever

• Is an arbovirus

• Transmitted by mosquitoes

• Composed of single-stranded RNA

• Has 4 serotypes (DEN-1, 2, 3, … The most important pathophysiological event in DHF/DSS is plasma leakage that causes pleu-ral effusion, ascites and occasionally death [1, 2]. 23. Classical dengue fever is observed more frequently in adults and occurs after an incubation of 4–7 days , . Dengue Fever is a mosquito-borne (Aedes aegytpi and rarely the Aedes albopictus species) disease with no apparent animal reservoir. Dengue virus infection is a major cause of morbidity, mortality, and economic hardship in the tropics and subtropics [1, 2]. Dengue virus (DENV), a member of the Flaviviridae family, causes the most widespread mosquito-borne viral infection in humans around the world today. After a person is bitten, the virus incubation period varies between 3 and 14 days, after which the person may experience early symptoms such as fever… Dengue is the most common and important mosquito-borne viral infection and can manifest as Dengue Fever (DF), which is often a self-limiting febrile illness or less commonly dengue hemorrhagic fever (DHF). Abstract. Hospital flow chart pdf, 68kb; Annex 5. RT-PCR using consensus primers and four type-specific downstream primers based on the NS3 gene can discriminate all four virus serotypes. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. Dengue fever, caused by infection with dengue virus, is not a new disease, but recently because of its serious emerging health threats, coupled with possible dire consequences including death, it has aroused considerable medical and public health concerns worldwide. There are many causes of fever. PATHOPHYSIOLOGY-OF-DENGUE-FEVER.pdf - PATHOPHYSIOLOGY OF DENGUE FEVER PREDISPOSING FACTORS Geographical areatropical\/subtropical Ages 15 years below Mostly adults and older children are affected, II. Pathophysiology of Dengue Encephalitis - Free download as Powerpoint Presentation (.ppt / .pptx), PDF File (.pdf), Text File (.txt) or view presentation slides online. Recent advances in electron microscopy and tomography have revealed distinct virus-induced endoplasmic reticulum (ER) structures unique for dengue virus (DV) and other flaviviruses in cell culture models, including hepatocytes. The most widely-cited hypothesis for the pathogenesis of severe dengue is antibody-dependent enhancement (ADE).. Persons who develop severe dengue infections are more likely to become hospitalized or die. (primarily Aedes aegypti) mosqui-toes [1]. pdf, 437kb Tools to support decision-making for the addition of the licensed dengue vaccine into a public immunization programme There are approximately five additional vaccine candidates under evaluation in clinical trials, including other live-attenuated vaccines, as well as subunit, DNA and purified inactivated vaccine candidates. The most common fever pathophysiology, however, is due to infection with invading organisms such as viruses and bacteria. T/C Dengue Hemorrhagic Fever/ Pleural Effusion, T/C Liver Pathology. Pathophysiology of dengue fever: Dengue infection is caused by bites of the female Aedes aegypti mosquito carrying Flavivirus. Download Free PDF. Clinical Course of Dengue Haemorrhagic Fever 15 7. Dengue haemorrhagic fever: questions of pathogenesis Mary Jane Cardosa The year under review has seen a remarkable proliferation of papers on dengue. Download Full PDF Package. • Severe dengue: dengue with any or more of the following scenarios: o Severe plasma leakage evidenced by hypovolemic shock and/or extravascular fluid accumulation with respiratory distress possibly with a abnormally high hematocrit value. Generally, infection with one serotype confers future protective immunity against that particular serotype but not against other serotypes. Today, dengue is considered one o … Dengue can affect anyone but tends to be more severe in people with compromised immune systems. They are RNA viruses that belong to the Flavivirus genus/Flaviviridae family, which also includes the yellow fever virus, West Nile virus, Japanese encephalitis virus, Zika virus, and the St Louis encephalitis virus. Symptoms of dengue fever — Get the gifts.] Download PDF. The clinical manifestations range from asymptomatic infection to undifferentiated fever, dengue fever and dengue hemorrhagic fever (DHF). Virology and Laboratory Diagnosis 4-6 3. Description. Countries or territories in which dengue or dengue haemorrhagic fever is known to occur, by WHO Region, 1975-1996 pdf, 26kb; Annex 2. Dengue hemorrhagic fever (DHF): A syndrome due to the dengue virus that tends to affect children under 10, causing abdominal pain, hemorrhage (bleeding) and circulatory collapse ().DHF starts abruptly with high continuous fever and headache plus respiratory and intestinal symptoms with sore throat, cough, nausea, vomiting, and abdominal pain. Dengue fever is now the talk of the country. Endothelial Nitric Oxide Pathways in the Pathophysiology of Dengue: A Prospective Observational Study. World Health Organization, Regional Office for South-East Asia. Pathophysiology. These viruses are related to the viruses that cause the West Nile infection and yellow fever. These altered ultrastructures serve as sites for viral replication. The pathophysiology of dengue hemorrhagic fever … DHF/DSS pathophysiology is not entirely unders-tood. The severe form of dengue fever, also called dengue hemorrhagic fever, can cause serious bleeding, a sudden drop in blood pressure (shock) and death. Dengue fever is an arboviral infection spread by the Aedes mosquito with a wide spectrum of presentations encompassing simple flu-like illness to hemorrhagic manifestations. A viraemic 876 Reprinted from AusTRAlIAn FAMIly PHysIcIAn Vol. Dengue fever is a disease transmitted by mosquitoes to the people and is commonly caused by flavivirus. As the death toll is rising day by day yet, the city corporation is taking not enough precautions lately. Acute pancreatitis as a complication of dengue fever. •Common name of the disease is ‘break-bone fever’ (Haddi Tod Bukhar (hDI taoD bauKar) Chapters. Thein TL, Wong J, Leo YS, et al. Outpatient flow chart pdf, 51kb; Annex 4. A, Revised dengue fever case 1classification,adapted from World Health Organization 2009.
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